Our lab aims to develop new prevention and treatment options to control disease caused by some of the most important human respiratory viruses, including influenza virus, respiratory syncytial virus, and betacoronaviruses.
Our lab has a major interest in some of the most important human respiratory viruses, including influenza A and B viruses, human respiratory syncytial virus, human parainfluenza virus 1 and 3 (hPIV1 and -3), and more recently, betacoronaviruses. Our prime aim is to develop new vaccines and nanobody-based antivirals against these viruses. A long-term aim is to develop these nanobody-based constructs as biologics that can be delivered by inhalation.
In addition, we aim to elucidate the antiviral mechanism of action of the interferon-induced mammalian virus restriction factors Mx1 and Mx2, taking advantage of interactomics tools that have been developed at the Center for Medical Biotechnology. These interactomics tools are also applied to identify and characterize interaction partners of RSV gene products.
Can Llamas help us to beat COVID-19?
To showcase the world-class scientific research of the Xavier Saelens Lab, you can discover their scientific papers in more detail.
We are always on the lookout for highly motivated colleagues to join our team. If you are interested, please contact us.
The Xavier Saelens Lab can only thrive thanks to the dedication and commitment of its people, no matter what their function or seniority.
To stay up to date in rapidly developing fields, scientists regularly interact with (international) colleagues. Conferences and other (scientific) events are an excellent way to facilitate such a continent-spanning knowledge exchange.