The Cytokine Receptor Lab focusses on a better understanding of receptor functioning at a mechanistic and biological level. Advancing new insights towards the clinic is our ultimate goal.
Research at the Cytokine Receptor Lab (CRL) is centered around four main themes: (1) mechanisms underlying receptor activation and the Jak/Stat pathway with the leptin receptor as a model system, (2) analysis of protein-protein interactions, from analytical programs to large-scale interactomics using our in-house developed MAPPIT platform, (3) the development of AcTakines, “Activity-on-Target” cytokines that display greatly reduced systemic toxicity, and (4) understand signaling downstream of Toll-like receptors by extensive semi-automated mutagenesis analysis and molecular modeling in combination with in-cellulo interaction assays.
To showcase the world-class scientific research of the Jan Tavernier Lab, you can discover their scientific papers in more detail.
We are always on the lookout for highly motivated colleagues to join our team. If you are interested, please contact us.
The Jan Tavernier Lab can only thrive thanks to the dedication and commitment of its people, no matter what their function or seniority.
To stay up to date in rapidly developing fields, scientists regularly interact with (international) colleagues. Conferences and other (scientific) events are an excellent way to facilitate such a continent-spanning knowledge exchange.